Horizon 2020 and Horizon Europe Programmes
QSAR Lab participates in international research and development projects funded under the European Union’s Horizon 2020 and Horizon Europe framework programmes.
iNAMed
Project ID: 101328775
Project title: Translating In Silico NAMs into Regulatory Practice for Medical Devices
Project acronym: iNAMed
Project website: under development
Project duration: 1 September 2026 – 31 May 2027
QSAR Lab joined the project: 1 September 2026
Project coordinator: QSAR Lab
Project objective: The project aims to lay the groundwork for incorporating in silico New Approach Methodologies (NAMs) into medical device conformity assessment under Regulation (EU) 2017/745 on medical devices (MDR).
iNAMed addresses the gap between the scientific maturity of AI-based computational toxicology and its still limited use in regulatory processes. The project focuses on transforming validated in silico NAMs into a regulatory-ready approach supported by structured validation, benchmarking and a clear pathway for regulatory integration.
The methodology will be demonstrated using an industrial reference case involving a continuous glucose monitoring sensor for intensive care unit patients. By reducing early-stage experimental work, shortening material optimisation cycles and strengthening safety assessment through human-relevant models, iNAMed will support the development of scalable, digital safety assessment for medical devices that meets regulatory needs.
EcoPilot
Project ID: 101295317
Project title: ECOPILOT: A Conversational PEF Copilot for Safe-and-Sustainable Furniture & Mattresses – From Data Gaps to Design Decisions
Project website: under development
Project duration: 1 June 2026 – 31 May 2029
QSAR Lab joined the project: 1 June 2026
Project coordinator: National Technical University of Athens (NTUA)
Project lead at QSAR Lab: Ewelina Bigus, PhD
Project objective: ECOPILOT aims to develop an AI-powered conversational tool that supports safe and sustainable design decisions by making environmental assessments more accessible and transparent.
Life Cycle Assessment (LCA) and Product Environmental Footprint (PEF) methods are essential to sustainable innovation. However, their practical application can be limited by data gaps, methodological complexity and the lack of easily accessible digital tools. ECOPILOT addresses these challenges by facilitating sustainability assessments and supporting their alignment with the Safe and Sustainable by Design (SSbD) framework.
The project will help small and medium-sized enterprises (SMEs) and innovators streamline assessment processes and generate data that enable more informed ecodesign decisions. By the end of the project, ECOPILOT is expected to reach Technology Readiness Level 6 (TRL 6), demonstrating the solution’s practical value in industry-relevant sustainability assessment processes.
EmerGO
Project ID: 101291654
Project title: EmerGO: A Platform for Tracking and Reducing Persistent and Emerging Pollutants Towards Zero Pollution in Food and Drink Systems
Project website: under development
Project duration: 1 June 2026 – 31 May 2030
QSAR Lab joined the project: 1 June 2026
Project coordinator: Fundació Eurecat (EUT)
Project lead at QSAR Lab: Ewelina Bigus, PhD
Project objective: EmerGO aims to support the identification, monitoring, prevention and reduction of persistent and emerging pollutants in the food and beverage sector through an integrated European platform.
Persistent and emerging pollutants remain a major challenge for safer and more sustainable food and beverage production systems. EmerGO addresses this challenge by supporting the development and validation of solutions that can help industry better understand pollution-related risks, improve assessment and monitoring processes and implement more effective pollution prevention and reduction strategies.
The project focuses on the food and beverage sector and aligns with European priorities related to Zero Pollution, Food 2030 and the sustainable transformation of industry. It will foster collaboration between science, industry and other stakeholders, helping to generate practical knowledge and tools for more transparent, evidence-based decision-making.
EmerGO aims to validate industry-relevant solutions and support the wider adoption of approaches that contribute to pollution reduction, regulatory compliance and consumer trust.
TriFluorium
Project ID: 101187492
Project title: Tribo-Reactor for fluorine circularity by urban mining
Project website: https://trifluorium.eu/
Project duration: 1 February 2025 – 31 January 2029
QSAR Lab joined the project: 1 February 2026
Project coordinator: AC2T Research GmbH (AC2T)
Project lead at QSAR Lab: Anita Sosnowska, PhD, Eng.
Project objective: TriFluorium significantly expands circular economy opportunities for highly persistent organofluorine waste streams, such as per- and polyfluoroalkyl substances (PFAS), including fluoropolymers. The project aims to recover fluorine safely, sustainably and efficiently in the form of stable inorganic fluorides that can be reused as industrial resources, such as fluorspar.
Fluoropolymers are essential to many critical and green technologies, including semiconductors, hydrogen production, fuel cells and electric vehicles. However, options for their treatment and recycling remain extremely limited. Fluorspar is included on the EU list of critical raw materials and is sourced primarily from outside the European Union. Its recycling rate is only 1% due to the lack of suitable technologies.
TriFluorium aims to demonstrate the principle of recycling organofluorine compounds through tribolysis at TRL 3, regardless of their chemical structure, molecular weight or liquid or solid form. The process will take place within a controlled tribocontact zone, where chemical reactions are initiated by mechanical stimuli.
In a single step, tribolysis is expected to break down highly stable organofluorine compounds, including perfluorinated substances, and convert them into stable inorganic products using safe reagents such as alkaline earth metal salts or oxides. The project will also develop a laboratory-scale Tribo-Reactor to validate the technology at TRL 4 and support further process scale-up.
Toxicological assessments and life cycle analyses will also be conducted to comprehensively evaluate the recycling process and the performance of the Tribo-Reactor. TriFluorium addresses urgent technological needs while supporting environmental, economic and societal objectives.
UPRISE
Project ID: 101156622
Project title: Unravelling ultrafine particulate matter and micro nano plastic’s mechanisms of impact on fetal health
Project website: https://www.uprise-horizon.eu/
Project duration: 1 January 2025 – 31 December 2029
Project coordinator: FUNDACION PARA LA INVESTIGACION DEL HOSPITAL UNI ES (Spain)
Project lead at QSAR Lab: Anita Sosnowska, PhD, Eng.
Project objective: UPRISE will characterise the complex mechanisms through which air pollution, particularly ultrafine particles (UFPs) and micro- and nanoplastics (MNPs), disrupts healthy fetal development and increases the risk of adverse birth outcomes (ABOs).
The project will develop exposure databases and assessment models for emerging pollutants that account for different exposure scenarios. This will provide a broader understanding of the sources of the substances being studied, their concentrations and their dispersion patterns.
Importantly, UPRISE will also include a clinical study involving pregnant women exposed to different levels of UFP and MNP pollution. The study will investigate potential modes of action leading to adverse birth outcomes. The results of transcriptomic, epigenetic and mitochondrial mutation analyses will be used to identify key events (KEs), including molecular initiating events (MIEs).
Based on these findings, causal models supported by weight-of-evidence (WoE) analysis will be developed to demonstrate the relationship between the uptake of these pollutants and the events leading to adverse birth outcomes.
PLANETS
Project ID: 101177608
Project title: Plasticizers, fLame-retardants and surfactANts: new alternatives validating the safE and susTainable by deSign approach
Project website: https://www.project-planets.eu/
Project duration: 1 November 2024 – 31 October 2028
Project coordinator: COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVE (France)
Project lead at QSAR Lab: Anita Sosnowska, PhD, Eng.
Project objective: PLANETS will demonstrate the applicability of the Safe and Sustainable by Design (SSbD) framework to the technical development of alternatives to three major classes of chemicals used in the chemical industry: plasticisers, flame retardants and surfactants. These alternatives will be developed to TRL 6 and incorporated into widely available consumer products at TRL 7.
The new molecules and products will be significantly safer for workers and consumers and will have a substantially lower environmental impact, while remaining economically viable and taking account of societal considerations across the three value chains. A central principle will be to eliminate hazardous substances by selecting safer alternatives and/or redesigning manufacturing processes to minimise the formation of hazardous substances.
Material efficiency, including the use of renewable and circular raw materials, efficient reactions and waste minimisation, as well as energy efficiency through the use of catalysts, fewer production stages and less energy-intensive manufacturing, will also be among the key design principles investigated within PLANETS.
AlChemiSStS
Project ID: 101178074
Project title: Alternative Chemicals and Materials integrating Safety, Sustainability, new Production technologies and Socio-economic aspects
Project website: https://www.alchemissts-project.eu/
Project duration: 1 November 2024 – 31 October 2028
Project coordinator: Instituto Tecnológico del Embalaje, Transporte y Logística – ITENE (Spain)
Project lead at QSAR Lab: Karolina Jagiełło, PhD, Eng.
Project objective: AlChemiSStS aims to demonstrate the application of the Safe and Sustainable by Design (SSbD) framework to the development and implementation of safer and more sustainable alternatives to substances such as surfactants, plasticisers and flame retardants. The substances targeted by the project are widely used in everyday products and are classified as substances of very high concern (SVHCs).
The project’s main objective will be achieved through several specific goals, including developing alternative substances, gathering robust evidence to demonstrate the SSbD concept and creating a certification methodology that supports the implementation of SSbD across industry.
NANO-ENGINE
Project ID: 101098944
Project title: A revolutionary cell programming platform based on the targeted nano-delivery of a transposon gene editing system
Project website: https://nano-engine.eu/
Project duration: 1 April 2023 – 31 March 2026
Project coordinator: Utrecht University
Project lead at QSAR Lab: Prof. Tomasz Puzyn
Project objective: NANO-ENGINE aims to develop a first-in-class, DNA-based, non-viral and targeted in vivo cell-programming technology that can be used to treat a wide range of diseases, including cancer and genetic disorders.
Within NANO-ENGINE, the consortium aims to characterise and test targeted nanoparticles, investigate small-scale synthesis and conduct proof-of-concept studies. This approach is intended to address the limitations of traditional cell therapies by reducing their costs, complexity and associated clinical risks, thereby making cell therapies significantly more accessible to patients worldwide.
CircEl-Paper
Project ID: 101070114
Project title: Circular Economy Applied To Electronic Printed Circuit Boards Based On Paper
Project website: https://circelpaper.eu/
Project duration: 1 September 2022 – 28 February 2026
Project coordinator: FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV
Project lead at QSAR Lab: Anita Sosnowska, PhD
Project objective: CircEl-Paper aims to increase e-waste recycling by making electronic products compatible with the well-established and widely accepted paper recycling process. The project focuses on widely used printed circuit board (PCB) technology and seeks to replace the conventional FR-4 composite core with a paper-based material.
To bring PCB technology into the circular economy, each stage of the process is being carefully analysed and alternative approaches are being developed to increase the proportion of materials that are recyclable, bio-based, derived from secondary raw materials or at least environmentally benign.
NOUVEAU
Project ID: 101058784
Project title: NOVEL ELECTRODE COATINGS AND INTERCONNECT FOR SUSTAINABLE AND REUSABLE SOEC
Project website: https://www.nouveau-project.eu/
Project duration: 1 September 2022 – 31 August 2025
Project coordinator: VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.
Project lead at QSAR Lab: Alicja Mikołajczyk, PhD
Project objective: NOUVEAU aims to develop innovative and environmentally friendly energy conversion technologies using new materials for solid oxide electrolysis cells (SOECs) and interconnects with reduced contents of rare earth elements (REEs), platinum-group metals (PGMs) and chromium (Cr).
The project aims to enable the production of higher-performance SOEC systems with lower manufacturing costs and reduced use of hazardous substances, in line with sustainable-by-design principles.
PROMISCES
Project ID: 101036449
Project title: Preventing Recalcitrant Organic Mobile Industrial chemicalS for Circular Economy in the Soil-sediment-water system
Project website: https://promisces.eu/
Project duration: 1 November 2021 – 30 April 2025
Project coordinator: Bureau de Recherches Géologiques et Minières
Project lead at QSAR Lab: Anita Sosnowska, PhD, Eng.
Project objective: PROMISCES aims to improve understanding of the sources and environmental fate of persistent pollutants that spread easily through the environment. The project seeks to enable a safe circular economy across the soil–sediment–water system by developing and testing, under real-world conditions, key technologies and innovations for monitoring, preventing and remediating industrial, persistent, mobile and potentially toxic pollutants (iPM(T)).
PROMISCES develops zero-pollution circular economy concepts for water and complex solid matrices in both the private and public sectors, with a particular focus on per- and polyfluoroalkyl substances (PFAS).
DIAGONAL
Project ID: 953152
Project title: Development and scaled Implementation of sAfe by design tools and Guidelines for multicOmponent aNd hArn nanomateriaLs
Project website: https://www.diagonalproject.eu/
Project duration: 1 May 2021 – 31 October 2024
Project coordinator: University of Burgos
Project lead at QSAR Lab: Alicja Mikołajczyk, PhD
Project objective: DIAGONAL aims to develop and implement safe-by-design tools and guidelines for next-generation multicomponent nanomaterials (MCNMs) and high-aspect-ratio nanomaterials (HARNs).
The project will develop new structure–property–function (SPF) and structure–property–hazard (SPH) models. These models will support a better understanding of how MCNMs and HARNs interact with the environment and enable assessment of the hazards they may pose to human health.
CompSafeNano
Project ID: 101008099
Project title: NanoInformatics Approaches for Safe-by-Design NanoMaterials
Project website: https://compsafenano.eu/
Project duration: 1 June 2020 – 31 May 2025
Project coordinator: NovaMechanics Ltd
Project lead at QSAR Lab: Anna Rybińska-Fryca, PhD
Project objective: CompSafeNano focuses on developing integrated and broadly applicable nanoinformatics models for a wide range of nanoforms, including materials and composites used and manufactured by industrial companies.
Regulatory authorities will also be able to use these integrated nanoinformatics models for risk assessment and informed decision-making. The project will additionally help strengthen scientific expertise and capacity in nanoinformatics.
RiskGONE
Project ID: 814425
Project title: Risk Governance of Nanotechnology
Project website: https://riskgone.nilu.no/
Project duration: 1 January 2019 – 28 February 2023
Project coordinator: NORSK INSTITUTT FOR LUFTFORSKNING STIFTELSE
Project lead at QSAR Lab: Anita Sosnowska, PhD, Eng.
Project objective: RiskGONE aims to support the standardisation and validation of methods for assessing nanomaterials through the evaluation, optimisation and pre-validation of Standard Operating Procedures (SOPs).
RiskGONE also aims to establish a self-sustaining Risk Governance Council representing EU Member States and public authorities, scientific experts, civil society and industry. In addition, the project will develop detailed guidance on nanomaterials, their classification and specific decision-making processes to support effective risk governance.
NanoSolveIT
Project ID: 814572
Project title: Innovative Nanoinformatics models and tools: towards a Solid Information System for Nanomaterial Risk Assessment (NanoSolveIT)
Project website: https://nanosolveit.eu/
Project duration: 1 January 2019 – 28 February 2023
Project coordinator: NovaMechanics Ltd
Project lead at QSAR Lab: Ewelina Wyrzykowska, PhD
Project objective: NanoSolveIT aims to introduce an innovative integrated approach to testing and assessment (IATA) for evaluating the safety and environmental impacts of nanomaterials.
Among its outcomes, NanoSolveIT will deliver innovative artificial intelligence (AI)-based methods for predicting (eco)toxicity and integrate them with emerging multiscale modelling methods and governance frameworks.
PATROLS
Project ID: 760813
Project title: Physiologically Anchored Tools for Realistic nanOmateriaL hazard aSsessment
Project website: https://www.patrols-h2020.eu/
Project duration: 1 January 2018 – 30 June 2021
Project coordinator: Swansea University
Project lead at QSAR Lab: Karolina Jagiełło, PhD, Eng.
Project objective: PATROLS aims to develop a set of reproducible and robust tests for predicting the long-term effects of nanomaterial hazards on human health and the environment.
These next-generation tests, designed as alternatives to studies using laboratory animals, will be based on in vitro testing with 3D models of selected tissues and on in silico methods.
National Grants
We carry out projects funded through national and regional programmes that support the development of our technologies, capabilities and activities in international markets.
Projekt 1
Application of Modern Biotechnological and Bioinformatics Techniques to the Development of Virus-Like Particles for Diagnostic and Therapeutic Purposes
Project title: Application of Modern Biotechnological and Bioinformatics Techniques to the Development of Virus-Like Particles for Diagnostic and Therapeutic Purposes
Grant agreement no.: FEPM.01.01-IP.03-0094/25-00
Total project value: PLN 5,481,058.32
Funding from the European Regional Development Fund: PLN 4,303,526.66
Eligible expenditure allocated to QSAR Lab: PLN 318,458.32
Funding allocated to QSAR Lab: PLN 254,766.66
Project activities: Development of an innovative diagnostic and therapeutic platform based on modified virus-like particles (VLPs). The work includes designing and synthesising VLPs, encapsulating therapeutic and diagnostic payloads, creating a ligand database and selecting ligands through bioinformatics methods using the PeptAIm platform, molecular modelling and in silico engineering, in vitro testing and producing optimised VLPs. The platform will be tested using glioblastoma multiforme as a reference case and TROP2 as a biomarker.
Target groups: Cancer patients, particularly patients with glioblastoma multiforme, patients with neurodegenerative diseases, the clinical community and the biotechnology and pharmaceutical sectors.
Project objective: To develop a platform using modified VLPs for targeted delivery of therapeutic substances and molecular diagnostics, with a particular focus on cancer treatment.
Project outcomes: Development of a technology combining the delivery of therapeutic substances with monitoring of treatment outcomes using molecular markers such as radionuclides and fluorophores.
Project results: A nanomedicine platform enabling targeted drug delivery, the development of molecular diagnostic tools and the design of biomarker-based therapies. The technology may also be further developed for other cancers and diseases requiring targeted treatments.
Project duration: 1 March 2026 – 28 February 2029
Co-funded by: European Regional Development Fund under the European Funds for Pomerania 2021–2027 programme, Measure 1.1 – Research and Innovation in Enterprises.
Project partnership: The project is implemented by NanoExpo Sp. z o.o. in partnership with QSAR Lab Sp. z o.o. and in international cooperation with Prof. Vincent Zoete’s team at the Swiss Institute of Bioinformatics.

Pomorski Broker Eksportowy 2030
Project title: Development of QSAR Lab Sp. z o.o.’s export activities under the “Pomeranian Export Broker 2030” grant project
Grant agreement no.: UDG-PBE.01.2025/043
Project no.: WNG-PBE.01.2025/043
Total project cost: PLN 78,046.24
EU funding: PLN 42,925.43
Own contribution: PLN 35,120.81
Project activities: Participation in international industry trade fairs as an exhibitor and the implementation of intensive promotional activities in foreign markets, particularly in the United States and South Korea.
Target groups: International business partners, companies and organisations interested in computational toxicology services and predictive models for (nano)materials.
Project objective: To achieve a sustained increase in export revenue, develop cooperation with international business partners and strengthen QSAR Lab’s position as a specialised provider of computational toxicology services and predictive models for (nano)materials.
Project outcomes: Increased recognition of QSAR Lab in foreign markets and strengthened export potential.
Project results: New business contacts, promotion of QSAR Lab’s services in international markets and further development of export cooperation.
Project duration: 15 December 2025 – 31 December 2026
Co-funded by: European Regional Development Fund.

SafeChemicals.guide
Project title: SafeChemicals.guide – AI-based software supporting the testing and registration of chemical substances, including active pharmaceutical ingredients (APIs), with consideration of alternative toxicity assessment methods
Grant agreement no.: FEPM.01.01-IP.03-0063/25
Total project cost: PLN 4,163,178.45
EU funding: PLN 3,216,351.71
Project activities: Development of AI-based software supporting the testing, safety assessment and registration of chemical substances, including active pharmaceutical ingredients used in the pharmaceutical sector, using alternative toxicity assessment methods.
Target groups: Companies and organisations operating in the chemical, pharmaceutical, cosmetic, food and biotechnology sectors.
Project objective: To develop a digital tool supporting chemical safety assessment and substance registration processes in the European Union.
Project outcomes: Greater potential for using artificial intelligence and alternative toxicity assessment methods in the testing, safety assessment and registration of chemical substances.
Project results: A functional prototype of the SafeChemicals.guide software.
Project duration: 1 March 2025 – 30 April 2029
Co-funded by: European Regional Development Fund.

Eurogrant Daiper2Value
Project title: Preparation of a Eurogrant application for the “Daiper2Value” project under the Horizon Europe Programme
Grant agreement no.: FENG.02.12-IP.02-0400/25
Total project cost: PLN 42,476.00
EU funding: PLN 42,476.00
Project objective: To prepare a funding application for the European “Daiper2Value” consortium project.
Project outcomes: Preparation and submission of the “Daiper2Value” Eurogrant application.
Project results: The Eurogrant application was submitted and its assessment was completed. Paper consumption was reduced by reusing previously printed paper during the application preparation process.

Eurogrant MOSAIC
Project title: Preparation of a Eurogrant application for the “MOSAIC” project under the Horizon Europe Programme
Grant agreement no.: FENG.02.12-IP.02-0395/25
Total project cost: PLN 42,476.00
EU funding: PLN 42,476.00
Project objective: To prepare a funding application for the European “MOSAIC” consortium project.
Project outcomes: Preparation and submission of the “MOSAIC” Eurogrant application.
Project results: The Eurogrant application was submitted and its assessment was completed. Paper consumption was reduced by reusing previously printed paper during the application preparation process.

Eurogrant ORACLE
Project title: Preparation of a Eurogrant application for the “ORACLE” project under the Horizon Europe Programme
Grant agreement no.: FENG.02.12-IP.02-0366/25
Total project cost: PLN 42,476.00
EU funding: PLN 42,476.00
Project objective: To prepare a funding application for the European “ORACLE” consortium project.
Project outcomes: Preparation and submission of the “ORACLE” Eurogrant application.
Project results: The Eurogrant application was submitted and its assessment was completed. Paper consumption was reduced by reusing previously printed paper during the application preparation process.

Eurogrant OPRAH
Project title: Preparation of a Eurogrant application for the “OPRAH” project under the Horizon Europe Programme
Grant agreement no.: FENG.02.12-IP.02-0364/25
Total project cost: PLN 42,476.00
EU funding: PLN 42,476.00
Project objective: To prepare a funding application for the European “OPRAH” consortium project.
Project outcomes: Preparation and submission of the “OPRAH” Eurogrant application.
Project results: The Eurogrant application was submitted and its assessment was completed. Paper consumption was reduced by reusing previously printed paper during the application preparation process.

Eurogrant POLARISS
Project title: Preparation of a Eurogrant application for the “POLARISS” project under the Horizon Europe Programme
Grant agreement no.: FENG.02.12-IP.02-0363/25
Total project cost: PLN 42,476.00
EU funding: PLN 42,476.00
Project objective: To prepare a funding application for the European “POLARISS” consortium project.
Project outcomes: Preparation and submission of the “POLARISS” Eurogrant application.
Project results: The Eurogrant application was submitted and its assessment was completed. Paper consumption was reduced by reusing previously printed paper during the application preparation process.

Eurogrant COCKTAIL
Project title: Preparation of a Eurogrant application for the “COCKTAIL” project under the Horizon Europe Programme
Grant agreement no.: FENG.02.12-IP.02-0315/25
Total project cost: PLN 42,476.00
EU funding: PLN 42,476.00
Project objective: To prepare a funding application for the European “COCKTAIL” consortium project.
Project outcomes: Preparation and submission of the “COCKTAIL” Eurogrant application.
Project results: The Eurogrant application was submitted and its assessment was completed. Paper consumption was reduced by reusing previously printed paper during the application preparation process.

Eurogrant NeuroTRIAL
Project title: Preparation of a Eurogrant application for the “NeuroTRIAL” project under the Horizon Europe Programme
Grant agreement no.: FENG.02.12-IP.02-0314/25
Total project cost: PLN 42,476.00
EU funding: PLN 42,476.00
Project objective: To prepare a funding application for the European “NeuroTRIAL” consortium project.
Project outcomes: Preparation and submission of the “NeuroTRIAL” Eurogrant application.
Project results: The Eurogrant application was submitted and its assessment was completed. Paper consumption was reduced by reusing previously printed paper during the application preparation process.

Eurogrant LESSpoll
Project title: Preparation of a Eurogrant application for the “LESSpoll” project under the Horizon Europe Programme
Grant agreement no.: FENG.02.12-IP.02-0313/25
Total project cost: PLN 42,476.00
EU funding: PLN 42,476.00
Project objective: To prepare a funding application for the European “LESSpoll” consortium project.
Project outcomes: Preparation and submission of the “LESSpoll” Eurogrant application.
Project results: The Eurogrant application was submitted and its assessment was completed. Paper consumption was reduced by reusing previously printed paper during the application preparation process.

Eurogrant HARMONIX
Project title: Preparation of a Eurogrant application for the “HARMONIX” project under the Horizon Europe Programme
Grant agreement no.: FENG.02.12-IP.02-0312/25
Total project cost: PLN 42,476.00
EU funding: PLN 42,476.00
Project objective: To prepare a funding application for the European “HARMONIX” consortium project.
Project outcomes: Preparation and submission of the “HARMONIX” Eurogrant application.
Project results: The Eurogrant application was submitted and its assessment was completed. Paper consumption was reduced by reusing previously printed paper during the application preparation process.

Eurogrant TriFluorium – Hop on
Project title: Preparation of a Eurogrant application for the “TriFluorium – Hop-on” project under the Horizon Europe Programme
Grant agreement no.: FENG.02.12-IP.02-0279/25
Total project cost: PLN 42,476.00
EU funding: PLN 42,476.00
Project objective: To prepare a funding application for the European “TriFluorium – Hop-on” consortium project.
Project outcomes: Preparation and submission of the “TriFluorium – Hop-on” Eurogrant application.
Project results: The Eurogrant application was submitted and its assessment was completed. Paper consumption was reduced by reusing previously printed paper during the application preparation process.

SPEKTRUM 2030
Project title: Project no. WNG-SPE.01.2025/055 implemented under the “Pomeranian Information and Advisory Services System – SPEKTRUM 2030” grant project
Grant agreement no.: UDG-SPE.01.2025/055
Total project cost: PLN 84,378.00
EU funding: PLN 41,160.00
Project objective, tasks and activities: The project aims to strengthen the company’s development potential through expert advisory support.
Four specialised advisory services will be provided:
Advice on an information security management system compliant with ISO 27001:2017.
Legal advice on protecting the company’s confidential information and know-how.
Analysis of financial and accounting processes and preparation of recommendations for improvements in this area.
Development of a management control model.
Target group: QSAR Lab Sp. z o.o.
Project outcomes and results: Implementation of organisational and process changes at QSAR Lab Sp. z o.o. through the provision of specialised advisory services.

SURPHACE
Project title: Surface-Enhanced Raman Spectroscopy for Pathogen Detection and the Development of Antipathogenic Coatings
Project acronym: SURPHACE
Grant agreement no.: M-ERA.NET3/2024/78/SURPHACE/2025
Total project cost: PLN 1,496,374.29
Funding from the National Centre for Research and Development: PLN 1,197,099.43
Project objective: SURPHACE aims to develop innovative antipathogenic materials (IAMs) with optimised surface properties through the intelligent combination of metal oxides, noble metals, metal–organic frameworks (MOFs), halides, ionic liquids and mesoporous materials.
Project outcomes: The project will develop materials for air filters and durable functional surfaces intended for sensitive environments, including healthcare settings. These materials will also provide smart, real-time pathogen detection.

Eurogrant SOL-CLEAR
Project title: Preparation of a Eurogrant application for the “Double Doctorate Platform aimed at the Development of Solar-Active Materials for Clean Environment and Green Energy” project (SOL-CLEAR) under the Horizon Europe Marie Skłodowska-Curie Actions Programme
Grant agreement no.: FENG.02.12-IP.02-0227/24
Total project cost: PLN 41,000.00
European Funds contribution: PLN 41,000.00
Project objective: To prepare a funding application for the “Double Doctorate Platform aimed at the Development of Solar-Active Materials for Clean Environment and Green Energy” project (SOL-CLEAR). The proposed project aims to design, develop and demonstrate the functional application of solar-active catalytic materials in energy and environmental technologies.
Eurogrant funding will support the QSAR Lab team involved in preparing the SOL-CLEAR proposal under the Horizon Europe Marie Skłodowska-Curie Actions Programme.
Action type: MSCA Doctoral Networks 2024
Call ID: HORIZON-MSCA-2024-DN-01

Eurogrant SOLIS
Project title: Preparation of a Eurogrant application for the “Solar-Driven Innovations: Sustainable Pathways for Fuel and Chemical Synthesis” project (SOLIS) under the COST Actions Programme
Grant agreement no.: FENG.02.12-IP.02-0184/24
Total project cost: PLN 41,000.00
European Funds contribution: PLN 41,000.00
Project objective: To prepare a funding application for the “Solar-Driven Innovations: Sustainable Pathways for Fuel and Chemical Synthesis” project (SOLIS). The proposed project focuses on innovative technologies that use solar energy in advanced reactors to facilitate the production of hydrogen, other fuels and chemicals.
Eurogrant funding will support the QSAR Lab team involved in preparing the SOLIS proposal under the European Cooperation in Science and Technology (COST) Programme.
Action type: Open Call
Call ID: OC-2024-1

Eurogrant CIRC-BUILD-EU
Project title: Preparation of a Eurogrant application for the “Designing and Promoting Integrative Innovative Tools, Products and Techniques Towards an Increased Circularity of Buildings” project (CIRC-BUILD-EU) under the Horizon Europe Programme
Grant agreement no.: FENG.02.12-IP.02-0169/24
Total project cost: PLN 41,000.00
European Funds contribution: PLN 41,000.00
Project objective: To prepare a funding application for the CIRC-BUILD-EU consortium project. The proposed project aims to develop, test and promote innovative tools, products and techniques for construction and renovation. These solutions will help extend the service life of buildings, facilitate their adaptation to changing user needs and support reuse and deconstruction, thereby optimising building life cycles and advancing the circular economy.
Eurogrant funding will support the QSAR Lab team involved in preparing the CIRC-BUILD-EU proposal under the Horizon Europe Framework Programme.
Action type: Research and Innovation Action (HORIZON-RIA)
Call ID: HORIZON-CL5-2024-D4-02-04

KFS
Agreement: Agreement no. 233/KFS/2022 on financing the continuing education costs of employees and the employer through the National Training Fund.
Total project cost: PLN 6,000.00
Project objective: The KFS project aims to help finance training services for employees of companies participating in the programme.
SPEKTRUM 2022
Project title: “SPEKTRUM – Pomeranian Advisory Services System” grant project
Project no.: WNG-SPE.03.00/006
Project duration: 1 July 2022 – 31 December 2022
Total project cost: PLN 47,970.00
Project objective: The SPEKTRUM project aims to enable small and medium-sized enterprises (SMEs) to purchase the business development services they need. Grants are awarded to cover part of the cost of purchasing specialised advisory services.

Eurogrant npGRASP
Project title: Preparation of an application for the “High-Resolution Multimodal Chemical Imaging Platform for Tracking Nanoplastics and Engineered Nanomaterials in the Life Cycle Analysis Framework” project (npGRASP) under the Horizon Europe Programme
Project no.: POIR.02.03.06-22-0014/22-00
Project duration: 1 March 2022 – 31 December 2022
Project value: PLN 23,250.00
Funding: PLN 23,250.00
Funding source: Sub-measure 2.3.6, Grants for Eurogrants, under the Smart Growth Operational Programme 2014–2020, co-funded by the European Regional Development Fund.
Project objective: To prepare a funding application for the European npGRASP consortium project. The proposed project aims to identify potential risks to human health and the environment arising from nanoplastics and other nanotechnology-based products present in the environment. It will also propose and evaluate advanced tools for assessing the risks associated with nanomaterials, particularly nanoplastics.
Project outcomes: Activities under npGRASP will develop this concept through scientific exchange, mentoring, training programmes and webinars for researchers employed by consortium members. QSAR Lab provides research and development services, primarily in the areas of nanomaterials and chemical safety.
Participation in npGRASP will enable the QSAR Lab scientific team to strengthen its expertise and establish new contacts, increasing the company’s capacity to implement research and development projects and enhancing its competitiveness in the international market.

ntellectual Property in Your Company
Project title:
Project no.: POIR.02.06.00-00-0001/19-00
Funding source: The agreement was implemented under the Smart Growth Operational Programme, Measure 2.6, “Non-competitive Project of the Patent Office of the Republic of Poland”, with funding from the European Regional Development Fund.
Total eligible costs: PLN 1,463.41
Total grant amount: PLN 1,317.07
Project objective: The project of the Patent Office of the Republic of Poland aims to develop entrepreneurs’ practical skills in using intellectual property protection, including industrial property protection, and to increase their awareness of the potential benefits arising from such protection.
Expected measurable outcomes: New applications for industrial property rights; exclusive rights granted for industrial property assets; licensing agreements concerning intellectual property rights; agreements concerning the transfer of intellectual property rights; internal company policies on intellectual property protection and management; agreements with employees containing intellectual property clauses; and other instruments, such as valuations of intangible assets.
PeptAlm
Project title: PeptAIm – an artificial intelligence-based platform for studying peptide–protein interactions using virtually generated peptide libraries
Project no.: POIR.01.01.01-00-1964/20
Project duration: 1 September 2021 – 31 December 2023
Project value: PLN 5,354,669.75
Project value allocated to QSAR Lab: PLN 3,034,834.75
EU funding: PLN 4,002,626.57
EU funding allocated to QSAR Lab: PLN 2,213,327.07
Project objective: To develop and implement the PeptAIm bioinformatics platform for creating molecular diagnostic tests. The platform enables the selection of ligands, particularly peptides, with high affinity for target proteins.
The software will primarily be used in molecular diagnostics and other scientific fields investigating protein–protein interactions, including ligand–receptor interactions. It will provide essential information about the sequence, three-dimensional structure and binding affinity of candidate peptides for a selected target receptor.

SPEKTRUM 2021
Project title: “SPEKTRUM – Pomeranian Advisory Services System” grant project
Project duration: 1 January 2021 – 31 May 2021
Total project cost: PLN 34,160.00
Funding from the European Funds budget: PLN 32,452.00
Own contribution: PLN 1,708.00
Project objective: The SPEKTRUM project aims to enable small and medium-sized enterprises (SMEs) to purchase the business development services they need. Grants are awarded to cover part of the cost of purchasing specialised advisory services.

Pomorski Broker Eksportowy
Project title: Support in the form of a foreign market broker service under the “Pomeranian Export Broker – Comprehensive Export Support System in the Pomeranian Voivodeship” project
QSAR Lab received support under two grant agreements:
1. Grant agreement no.: UDG-PBE.04.2020/063
Scope of support: Funding for the implementation of the “Expansion of QSAR Lab Sp. z o.o.’s Services into Foreign Markets” project in the form of financial support for the participation of an SME in trade fairs.
Project objective: To support the company’s development and expand its sales markets, particularly within Europe. The expected result was an expanded international customer base and increased recognition of QSAR Lab.
Project duration: 18 December 2020 – 30 September 2022
Total project cost: PLN 78,962.92
EU funding: PLN 39,377.96
Own contribution: PLN 39,377.96
2. Agreement no.: DRP/51/2020
Scope of support: Provision of a foreign market broker service.
The support included research and analysis of the Swedish market, an assessment of business opportunities, assistance in initiating business contacts and support in building business relationships through meetings with potential partners in Sweden.
Estimated value of the foreign market broker service: PLN 70,000.00
Programme: Regional Operational Programme for the Pomeranian Voivodeship 2014–2020.
Nano-QSAR Toolbox ZnO SiO2
Project no. POIR.01.01.01-00-0779/20 “Development and implementation of the Nano-QSAR Toolbox platform enabling computer prediction of physicochemical properties, toxicity and ecotoxicity of ZnO and SiO2 nanoparticles”
Realization date: 01.11.2020 – 30.06.2023 r.
Project value: 2 713 734,28 zł
EU funding: 2 127 048,52 zł
Funding: “Fast Track” competition implemented under Sub-measure 1.1.1. “Industrial research and development work carried out by enterprises” of the Smart Growth Operational Program 2014-2020 by the National Center for Research and Development.
Aim: development and implementation of the Nano-QSAR Toolbox platform, enabling computer prediction of the physico-chemical properties, toxicity, and ecotoxicity of zinc oxide and silicon dioxide nanoparticles in the context of risk assessment required when registering new chemical substances before their introduction to the market. The Nano-QSAR computer modeling method will enable the prediction of selected physicochemical, toxicological and ecotoxicological properties and the generation of reports presenting the results consistent with the regulatory area in which a given nanoparticle will be used.

Nano-QSAR Toolbox TiO2
Projekt nr POIR.01.01.01-00-0372/19 pn. „Nano-QSAR Toolbox – platforma do komputerowego przewidywania właściwości fizykochemicznych, toksyczności i ekotoksyczności nanocząstek ditlenku tytanu”
Termin realizacji: 01.12.2019 – 30.11.2022 r.
Wartość projektu: 2 157 705,00 zł
Kwota dofinansowania z UE: 1 695 287,75 zł
Dofinansowanie: Konkurs „Szybka Ścieżka” realizowany w ramach Poddziałania 1.1.1. „Badania przemysłowe i prace rozwojowe realizowane przez przedsiębiorstwa” Programu Operacyjnego Inteligentny Rozwój 2014-2020 przez Narodowe Centrum Badań i Rozwoju.
Cel projektu: opracowanie i wdrożenie platformy Nano-QSAR Toolbox, umożliwiającej komputerowe przewidywanie właściwości fizyko-chemicznych, toksyczności i ekotoksyczności nanocząstek ditlenku tytanu w kontekście oceny ryzyka wymaganego przy rejestracji nowych substancji chemicznych przed ich wprowadzeniem na rynek. Metoda modelowania komputerowego Nano-QSAR umożliwi przewidywanie wybranych właściwości fizykochemicznych, toksykologicznych i ekotoksykologicznych oraz wygenerowanie raportów prezentujących wyniki, zgodnych z obszarem regulacji, w których dana nanocząstka zostanie wykorzystana.

Public Procurement Projects
QSAR Lab carries out specialized research and expert projects commissioned by leading European Union agencies and institutions, including ECHA and EFSA. We combine scientific expertise with regulatory experience to support the development of modern methods and frameworks for assessing the safety of chemicals, nanomaterials and products across the food chain.
Projekt 1
iNAMs4NGRA
Project title: Developing provisions for guidance on New Approach Methodologies data integration and implementing hypothesis-driven Next-Generation Risk Assessment in the food and feed chain, with a focus on nanotechnology
Project acronym: iNAMs4NGRA
Procurement reference: EFSA/2025/OP/0005
Contracting authority: European Food Safety Authority (EFSA)
Coordinator: QSAR Lab Ltd.
Consortium partners: German Federal Institute for Risk Assessment (BfR) – partner and WP1 co-lead; Italian National Institute of Health (ISS) – partner and WP2 co-lead; French Agency for Food, Environmental and Occupational Health & Safety (ANSES); National Institute for Public Health and the Environment (RIVM); and Wageningen Food Safety Research (WFSR).
QSAR Lab’s role: Project coordinator and co-lead of WP1 and WP2.
Project objective: iNAMs4NGRA aims to consolidate knowledge on the use of data from New Approach Methodologies (NAMs) in food and feed risk assessment, with a particular focus on nanomaterials. The project will establish the foundations for a robust, hypothesis-driven Next-Generation Risk Assessment (NGRA) framework and support experts in using NAMs data effectively in regulatory decision-making.
Project activities: The project will gather experience from published EFSA case studies and relevant international initiatives, identify existing good practices and develop preliminary recommendations for integrating NAMs data with conventional animal study data and human data, where available. Together with key stakeholders, the consortium will also develop the foundations for a framework and cross-cutting guidance on NAMs data integration and the implementation of hypothesis-driven NGRA.
Particular attention will be given to issues relevant to nanomaterials, including physicochemical characterisation, the behaviour of nanomaterials in biological fluids, toxicokinetics and toxicity screening.
Target groups: Risk assessment experts, regulatory institutions and stakeholders involved in developing, evaluating and applying NAMs in food and feed safety assessment, including the assessment of nanomaterials.
Project outcomes: The project will strengthen the scientific foundations for integrating NAMs data into the risk assessment of chemicals and nanoscale materials. It will support a more transparent, reproducible and consistent use of NAMs in regulatory processes.
Expected results: A structured review of existing experience and good practices, preliminary recommendations for NAMs data integration and the foundations for a framework and cross-cutting guidance supporting hypothesis-driven NGRA in the food and feed sector.

SC01 ECHA/2024/0205
Project title: Methodology Development and Data Generation for the Assessment and Grouping of Nanoforms
Project no.: ECHA/2022/502 – Lot 2
Specific contract: SC01 ECHA/2024/0205
Contracting authority: European Chemicals Agency (ECHA)
Consortium: QL_NAM_NANO_2023
Consortium lead: QSAR Lab Sp. z o.o.
Project partners: University of Łódź; Institute for Medical Research and Occupational Health in Zagreb; and European Regional Centre for Ecohydrology of the Polish Academy of Sciences.
Project duration: 2023–2029
Project status: Ongoing
Project website: https://erce.unesco.lodz.pl/rozwoj-metodologiczny-i-generowanie-danych-do-oceny-i-tworzenia-zestawow-nanoform/
Official documentation: https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/tender-details/docs/etender/13398/13398_159983_EN-Annex%202.2%20Technical%20Specifications_Lot%202_ENG_V1.pdf
Project description: The multiannual framework contract supports the European Chemicals Agency in developing methodologies and generating the data needed to assess and establish sets of nanoforms. Its main objective is to develop a scientifically robust and regulatorily relevant framework for determining the identity and similarity of nanoforms and justifying their grouping for joint hazard, exposure and risk assessment under REACH.
The consortium combines expertise in nanomaterial synthesis and physicochemical characterisation, toxicology, ecotoxicology, computational modelling, machine learning and artificial intelligence. QSAR Lab leads the consortium and coordinates the development of approaches that integrate experimental and in silico data.
The scope of the framework contract includes expert support concerning the regulatory use of New Approach Methodologies (NAMs) for nanoforms, reviews of available methods and data, identification of knowledge gaps, development or adaptation of testing methods and generation of experimental data where necessary.
The project also includes the development of a tiered NAMs-based testing framework. Tier 1 screening will support the creation of sets of similar nanoforms, while Tier 2 may cover standard information requirements in cases where additional data are needed.
The framework will be evaluated through at least four case studies involving chemically diverse nanoforms. Stakeholder consultations and external scientific reviews will also be conducted to strengthen the quality and regulatory relevance of the results.
The project will provide a practical foundation for more reliable and efficient safety assessment and registration of nanoforms. By supporting scientifically justified grouping, read-across and targeted testing strategies, the framework may help reduce unnecessary separate assessments of individual nanoforms and the use of vertebrate animals without increasing uncertainty about potential risks to human health and the environment.
The detailed scope of work and deliverables for individual tasks is defined in the specific contracts concluded under the framework agreement.

ECHA-62-2022
Project title: Nanomaterial-Specific Alternative Methods for Human Health Hazard and Safety Assessment under Different EU Regulations, Considering the Existing Animal Testing Bans for Cosmetics and Their Ingredients
Project no.: ECHA-62-2022
Contracting authorities: European Chemicals Agency (ECHA) and European Union Observatory for Nanomaterials (EUON)
Contractor: QSAR Lab Sp. z o.o.
Project duration: 2022–2023
Project status: Completed
Project website: https://euon.echa.europa.eu/documents/2435000/3268573/ECHA-62-2022_NAMs_01AUG2023.pdf/7e66ea6b-3a76-fece-4b1e-3875ff3d8849?download=true
Project team: Karolina Jagiełło, Anita Sosnowska, Maciej Stępnik, Maciej Gromelski and Karolina Płonka.
Project description: The study reviewed and systematically organised New Approach Methodologies (NAMs) that could be applied to the human health hazard and safety assessment of engineered nanomaterials. It considered requirements arising from REACH, the Biocidal Products Regulation, the Cosmetics Regulation and EU legislation concerning food and the food chain, including the applicable animal testing bans for cosmetics and their ingredients.
QSAR Lab conducted a structured literature review, mapped regulatory-relevant endpoints and surveyed 25 experts representing academia, industry and regulatory institutions. The analysis covered scientific publications, OECD guidance and documents, ISO standards, resources from the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM), Standard Operating Procedures, Adverse Outcome Pathways and results from European research projects.
Within the defined scope of the review and based on information collected up to 30 December 2022, 221 NAMs were identified: 8 regulatorily accepted methods specific to nanomaterials, 6 nanomaterial-specific methods undergoing validation, 120 methods under development, 69 accepted methods developed for conventional chemicals and 18 such methods undergoing validation.
The findings revealed a significant gap between method development and regulatory implementation. The report identified priority areas including genotoxicity, carcinogenicity, dermal and oral absorption, inhalation toxicity, neurotoxicity and toxicokinetics.
The report also recommended adapting existing validated methods to nanomaterials, developing appropriate exposure and nanomaterial characterisation protocols and increasing the availability of data supporting the development and validation of in silico methods.


