Risk assessment of chemicals & (nano)materials
Each manufactured chemical substance, drug, or (nano)material that enters the natural environment and the human body may pose a risk on many levels. It is important not only to design consciously but also to predict the behavior and fate of chemicals effectively.
QSAR Lab experts have been specializing for years in developing forecasting models enabling a comprehensive assessment of the risk posed by new materials (including nanomaterials) to the natural environment and to human health and life.
The purpose of a chemical risk assessment is to fully understand the nature and likelihood of a chemical’s potential adverse effects on health or the environment. It takes into account both hazard and exposure.
QSAR Lab provides a comprehensive risk assessment of a given substance, covering the three most important elements:
- Hazard prediction
Predicting dose-response relationships (LD50/LC50, EC50, TD50, etc.), determining the relationship between the amount of exposure to a hazard and the probability and severity of side effects.
- Exposure assessment
Determining the extent to which exposure actually occurs.
- Risk characteristics
Combining hazard prediction and exposure assessment information to reach conclusions on the nature and magnitude of the risk and, if appropriate, implement additional risk management measures.
Risk assessment currently forms the basis for regulatory decisions regarding industrial chemicals, pesticides, pharmaceuticals, cosmetics, food additives, and food contact substances in developed countries.