Research

Research conducted by QSAR Lab is aimed at developing a set of computer tools that enable us to perform, relatively quickly, comprehensive risk assessments of new materials (including nanomaterials) for human health and the environment.

QSAR Lab’s R&D activity focuses on the development of computer-enabled methods and the application of those methods to expand knowledge in the following fields:

• modeling of material properties at the electronic, atomic and mesoscopic levels,
• assessing (eco)toxicity and the end state of materials in the environment,
• understanding the role of the structural properties of materials in inducing responses at the ‘-omic’ level
        (e. transcriptomic, proteomic, metabolomic etc.),fundamental causes of adverse effects observed under the proposed Adverse Outcome Pathways (AOP),
• explaining the role of biophysicochemical interactions in the mechanism of material toxicity,
• active participation in adapting risk assessment guidelines to the specificity of (nano) materials in the regulatory context.